HPS — Hantavirus pulmonary syndrome

Andes virus (ANDV)

Andes virus is the dominant hantavirus in the Southern Cone of South America. It is the only hantavirus species with documented person-to-person transmission, which is why public health agencies place travel-linked clusters such as the MV Hondius event under heightened surveillance.

Primary rodent host
Long-tailed pygmy rice rat (Oligoryzomys longicaudatus) and related Oligoryzomys species
Geographic range
Argentina, Chile, southern Brazil, Uruguay, Bolivia, Paraguay
Case-fatality rate
30 to 50 percent in confirmed HPS cases
Incubation
7 to 39 days, median around 14 to 17 days
Discovered
1995, Bariloche outbreak in Argentina

Transmission

Inhalation of aerosolised rodent excreta. Andes virus is the only hantavirus with documented limited person-to-person transmission, especially within households and healthcare settings during the early symptomatic phase.

Key facts

  • Causes severe HPS with rapid progression to cardiopulmonary collapse
  • Person-to-person spread is rare but documented for ANDV, especially in close household contacts
  • Most cases occur in rural and peri-urban settings with rodent exposure during summer and autumn
  • Treatment is supportive intensive care; ECMO improves survival in severe cases

Reporting agencies

WHO Disease Outbreak NewsPAHOArgentina MSALChile MINSAL
Sources: WHO, ECDC, U.S. CDC, PAHO and peer-reviewed virology and epidemiology literature.
Disclaimer: Information is for educational purposes only. Always consult a qualified healthcare professional for clinical advice.