Dobrava-Belgrade virus (DOBV)
Dobrava-Belgrade virus causes the most severe form of HFRS in Europe. The Apodemus flavicollis lineage is associated with higher case-fatality than Puumala or the Apodemus agrarius lineage.
- Primary rodent host
- Yellow-necked mouse (Apodemus flavicollis) and striped field mouse (Apodemus agrarius)
- Geographic range
- Balkans and Eastern Europe
- Case-fatality rate
- Up to 12 percent for the Apodemus flavicollis (DOBV-Af) lineage
- Incubation
- 2 to 4 weeks
- Discovered
- 1992, Dobrava, Slovenia
Transmission
Aerosolised rodent excreta in rural homes, sheds and forests. No documented person-to-person spread.
Key facts
- ▪ Severe HFRS with bleeding, shock and acute kidney injury
- ▪ Most reports come from Slovenia, Croatia, Bosnia and Herzegovina, Serbia and Greece
- ▪ Often confused with leptospirosis on initial clinical work-up
- ▪ Surveillance is coordinated through ECDC and national health institutes
Reporting agencies
ECDCNIJZ SloveniaHZJZ Croatia
Sources: WHO, ECDC, U.S. CDC, PAHO and peer-reviewed virology and epidemiology literature.
Disclaimer: Information is for educational purposes only. Always consult a qualified healthcare professional for clinical advice.
Disclaimer: Information is for educational purposes only. Always consult a qualified healthcare professional for clinical advice.