HFRS — Hemorrhagic fever with renal syndrome (moderate form)

Seoul virus (SEOV)

Seoul virus is the only hantavirus with a worldwide distribution because its rodent host follows global shipping routes. Recent clusters in pet rat keepers have prompted CDC and UKHSA advisories.

Primary rodent host
Norway rat and black rat (Rattus norvegicus, Rattus rattus)
Geographic range
Worldwide, wherever Norway and black rats are established
Case-fatality rate
1 to 2 percent
Incubation
2 to 4 weeks
Discovered
1980, Seoul, South Korea

Transmission

Aerosolised excreta from urban and pet rats. Outbreaks in pet rat owners have been reported in the United States and the United Kingdom.

Key facts

  • Causes moderate HFRS with prominent liver involvement
  • Pet rat exposure is a recognised risk in the United States and the United Kingdom
  • Found in any city with significant rat populations, including ports and waste sites
  • Surveillance often relies on serology of high-risk groups (pest control, ratteries)

Reporting agencies

CDCUKHSAWHO
Sources: WHO, ECDC, U.S. CDC, PAHO and peer-reviewed virology and epidemiology literature.
Disclaimer: Information is for educational purposes only. Always consult a qualified healthcare professional for clinical advice.