Cepas
Cepas de hantavírus e doenças associadas
Os hantavírus são uma família de vírus transmitidos por roedores que causam duas síndromes humanas distintas: SPH nas Américas e FHSR na Europa e Ásia. Cada cepa tem um hospedeiro roedor, área geográfica e perfil clínico específicos.
Andes virus (ANDV)
HPS · Argentina, Chile, southern Brazil, Uruguay, Bolivia, Paraguay
Andes virus is the dominant hantavirus in the Southern Cone of South America. It is the only hantavirus species with documented person-to-person transmission, which is why public health agencies place travel-linked clusters such as the MV Hondius event under heightened surveillance.
- Hospedeiro
- Long-tailed pygmy rice rat (Oligoryzomys longicaudatus) and related Oligoryzomys species
- Letalidade
- 30 to 50 percent in confirmed HPS cases
Sin Nombre virus (SNV)
HPS · Western United States, Canada, northern Mexico
Sin Nombre virus is the most common hantavirus in North America and the cause of the original 1993 Four Corners hantavirus pulmonary syndrome outbreak. Deer mouse populations track precipitation cycles, so case counts spike after wet years.
- Hospedeiro
- Deer mouse (Peromyscus maniculatus)
- Letalidade
- 30 to 40 percent in confirmed HPS cases
Puumala virus (PUUV)
HFRS · Finland, Sweden, Norway, Belgium, France, Germany, Russia
Puumala virus causes a mild form of HFRS known as nephropathia epidemica (NE). Most cases are reported from Fennoscandia, where bank vole population peaks every three to four years drive outbreak years.
- Hospedeiro
- Bank vole (Myodes glareolus)
- Letalidade
- Less than 1 percent
Hantaan virus (HTNV)
HFRS · China, South Korea, eastern Russia
Hantaan virus is the prototype hantavirus and the cause of severe HFRS in East Asia. It remains a leading cause of hospitalised infectious nephritis in rural China and Korea.
- Hospedeiro
- Striped field mouse (Apodemus agrarius)
- Letalidade
- 5 to 15 percent
Seoul virus (SEOV)
HFRS · Worldwide, wherever Norway and black rats are established
Seoul virus is the only hantavirus with a worldwide distribution because its rodent host follows global shipping routes. Recent clusters in pet rat keepers have prompted CDC and UKHSA advisories.
- Hospedeiro
- Norway rat and black rat (Rattus norvegicus, Rattus rattus)
- Letalidade
- 1 to 2 percent
Dobrava-Belgrade virus (DOBV)
HFRS · Balkans and Eastern Europe
Dobrava-Belgrade virus causes the most severe form of HFRS in Europe. The Apodemus flavicollis lineage is associated with higher case-fatality than Puumala or the Apodemus agrarius lineage.
- Hospedeiro
- Yellow-necked mouse (Apodemus flavicollis) and striped field mouse (Apodemus agrarius)
- Letalidade
- Up to 12 percent for the Apodemus flavicollis (DOBV-Af) lineage